Grid

.container {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr 1fr;
  grid-auto-rows: 100px;
}
.item1 {
  grid-column: 1 / 3;
  grid-row: 1 / 3;
  background-color: #f26561;
}
.container > div:nth-child(1) {
  background-color: #5bc292;
}
.container > div {
  display: flex;
  justify-content: center;
  align-items: center;
  font-size: 24px;
  color: #00000;
  border: 1px solid red;
}

.container {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr 1fr;
  grid-auto-rows: 100px;
}
.item1 {
  grid-column: 1 / -1;
  grid-row: 1 / span 2;
  background-color: #f26561;
}
.container > div:nth-child(1) {
  background-color: #5bc292;
}
.container > div {
  display: flex;
  justify-content: center;
  align-items: center;
  font-size: 24px;
  color: #00000;
  border: 1px solid red;
}

.container {
  display: grid;
  grid-template-columns: 1fr 1fr 1fr 1fr;
  grid-auto-rows: 100px;
}
.item1 {
  grid-column: 2;
  grid-row: 2;
  background-color: #f26561;
}
.container > div:nth-child(1) {
  background-color: #5bc292;
}
.container > div {
  display: flex;
  justify-content: center;
  align-items: center;
  font-size: 24px;
  color: #00000;
  border: 1px solid red;
}